Table 4.

Risk of DTC associated with the combination of rs3752874 and rs844107 of THRB and different TG and TRHR polymorphisms.

	THRB rs3752874
CC		CT+TT
	Controls/cases	OR (95% CI)	Controls/cases	OR (95% CI)	P for interaction
TG
rs2076740					0.014
CC	128/106	1.00	44/46	1.17 (0.71–1.93)
CT	147/123	0.94 (0.65–1.34)	65/43	0.77 (0.48–1.23)
TT	40/44	1.30 (0.78–2.16)	30/9	0.35 (0.16–0.79)
TRHR
rs4129682					0.0024
CC	85/83	1.00	44/17	0.41 (0.21–0.76)
CT	163/154	0.93 (0.63–1.37)	77/63	0.76 (0.48–1.20)
TT	80/50	0.57 (0.36–0.92)	25/28	1.14 (0.61–2.15)
	THRB rs844107
	AA		AG+GG
	Controls/cases	OR (95% CI)	Controls/cases	OR (95% CI)	P for interaction
TG
rs2076740					0.099
CC	66/55	1.00	95/95	1.11 (0.69–1.78)
CT	81/75	0.97 (0.59–1.59)	127/86	0.76 (0.48–1.21)
TT	18/23	1.58 (0.76–3.29)	51/30	0.65 (0.36–1.17)
TRHR
rs4129682					0.11
CC	47/51	1.00	76/46	0.58 (0.33–1.01)
CT	87/81	0.84 (0.50–1.40)	146/132	0.79 (0.49–1.26)
TT	42/26	0.52 (0.27–1.00)	60/52	0.74 (0.42–1.29)

OR, odds ratio adjusted for age and gender; CI, confidence interval.