Table 3.
Eight years changes of BNP and associations of baseline parathyroid hormone quartiles with BNP after 8 years of follow-up in 278 subjects.
| Serum parathyroid hormone (pmol/l) | |||||
|---|---|---|---|---|---|
| Mean and range (min–max) | 1st Quartile 3.9 (2.5, 4.8) | 2nd Quartile 5.1 (4.1, 6.0) | 3rd Quartile 6.2 (4.7, 7.9) | 4th Quartile 8.8 (5.8, 14.7) | P trend |
| n | 66 | 72 | 73 | 67 | |
| Absolute BNP changes (pmol/l)a | 12.8±15.0 | 16.4±25.0 | 15.8±26.8 | 15.0±26.3 | 0.334 |
| Regression coefficients | |||||
| Model 1 | Reference | 4.5 (−4.0, 13.0)b | 2.7 (−5.8, 11.2) | 4.2 (−4.4, 12.9) | 0.445 |
| Model 2 | Reference | 1.7 (−5.6, 9.0) | 2.0 (−5.1, 9.4) | −2.5 (−10.1, 5.2) | 0.556 |
| Model 3 | Reference | 2.0 (−5.4, 9.3) | 2.2 (−5.2, 9.6) | −2.3 (−10.2, 5.6) | 0.603 |
BNP, B-type natriuretic peptide. Model 1, adjusted for age; model 2, model 1+baseline BNP, smoking, outdoor activities, body mass index, triglycerides, and high density lipoprotein cholesterol; model 3, model 2+eGFR, 25(OH)D.
a
Baseline BNP adjusted to follow-up BNP by adding 2.66 pmol/l to baseline BNP (17); presented as mean changes±s.d. in pmol/l.
b
A positive regression coefficient implies higher BNP.