Table 1.

Pathway analysis using the gene signature discovered during the identification of sepsis subtypes

Pathway	P-value	Bonferonni
Inflammation mediated by chemokine and cytokine signaling pathway	2.70E-08	0.0000048
Toll receptor signaling pathway	7.66E-05	0.0135
T cell activation	4.75E-03	0.835
p38 MAPK pathway	5.38E-03	0.946
JAK/STAT signaling pathway	7.59E-03	1
Beta3 adrenergic receptor signaling pathway	0.02	1
Integrin signalling pathway	0.02	1
B cell activation	0.02	1
Interferon-gamma signaling pathway	0.02	1
Opioid prodynorphin pathway	0.02	1
Opioid proenkephalin pathway	0.02	1
5HT4 type receptor mediated signaling pathway	0.02	1
Opioid proopiomelanocortin pathway	0.03	1
Salvage pyrimidine deoxyribonucleotides	0.03	1
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway	0.04	1
Nicotinic acetylcholine receptor signaling pathway	0.04	1
Parkinson disease	0.04	1
Beta2 adrenergic receptor signaling pathway	0.04	1
Beta1 adrenergic receptor signaling pathway	0.04	1
5HT1 type receptor mediated signaling pathway	0.04	1