Table 2.
Comparison of clinical attributes between the two sepsis subtypes defined by gene expression profiles
| Clinical attribute | Subtype 1 | Subtype 2 | P-value |
|---|---|---|---|
| Mortality (%) | 36 | 33 | 1 |
| Male (%) | 60 | 64 | 0.80 |
| Severe sepsis (%) | 36 | 9 | 0.009 |
| Septic shock (%) | 44 | 64 | 0.13 |
| Ventilated (%) | 60 | 56 | 0.80 |
| Dialysis (%) | 8 | 18 | 0.31 |
| Vasopressors (%) | 28 | 49 | 0.13 |
| Gram positive (%)* | 62 | 42 | 0.26 |
| Gram negative (%)* | 57 | 71 | 0.38 |
| Length of stay (days) | 45 | 31 | 0.23 |
| Age | 63 | 66 | 0.56 |
| APACHE II | 19 | 19 | 0.78 |
| SAPS II | 39 | 45 | 0.10 |
| APACHE III | 70 | 70 | 0.93 |
*Percentage of patients who were culture positive. Four patients from each subtype had both Gram positive and Gram negative organisms isolated.