Table 1.

Measured study drug concentrations in the control jars and the extracorporeal membrane oxygenation circuits at 5 minutes and at 1, 6, 12, and 24 hours

Drug, units of concentration	5 minutes		1 hour		6 hours		12 hours		24 hours
	C	E	C	E	C	E	C	E	C	E
Fentanyl, ng/mL
Median	27	1	25	0.4	26	0.1	22	0.1	22	0
Range	26-29	1-1	24-25	0.2-0.5	26-28	0-0.2	20-24	0-0.2	20-24	0-0.1
Morphine, ng/mL
Median	136	7	139	8	137	8	139	8	135	8
Range	134-140	6-7	132-141	7-9	134-140	8-9	135-143	8-8	134-141	7-9
Midazolam, ng/mL
Median	134	175	131	117	138	59	124	42	128	31
Range	126-155	144-356	124-137	109-261	127-147	54-124	117-132	41- 96	120-131	30-61
Vancomycin, μg/mL
Median	71	73	70	73	72	71	72	71	69	67
Range	66-80	67-83	69-76	70-86	67-76	69-74	68-74	68-71	67-70	64-70
Meropenem, μg/mL
Median	18	15	17	14	14	10	11	6	7	3
Range	17-18	11-16	16-18	10-15	13-15	7-11	11-11	4-8	7-8	2-5

C, control jars; E, extracorporeal membrane oxygenation circuits.