Figure 5.
Flow cytometry analysis of IFN-γ secretion in whole blood by CD56bright and CD56dim natural killer (NK) cell subsets after overnight ex vivo stimulation. (A) IL-15 + IL-18; (B) IL-15 + IL-18 + LPS; (C) IL-15 + IL-18 + CpG-DNA; (D) IL-15 + IL-18 + heat-killed S. aureus (HKSA). Median and interquartile range are shown for each group. *P < 0.05; ***P < 0.001 for comparison between healthy donors and patients. MFI, mean fluorescence intensity.