Table 3.
Independent factors associated with 100-day survival, by multivariate Cox proportional hazards regression analysis
| Patients (n) | Mortality within 100 days, n (%) | Median survival of fatal cases (days) | P value | Hazards ratio | 95% confidence interval | |
|---|---|---|---|---|---|---|
| Age | ||||||
| ≥70 | 60 | 34 (56.7) | 50 | 0.32 | 1.75 | 0.58 to 5.31 |
| <70 | 17 | 6 (35.3) | 16 | |||
| APACHE score | ||||||
| ≥20 | 52 | 33 (63.5) | 36 | 0.01 | 3.75 | 1.34 to 10.44 |
| <20 | 25 | 7 (28.0) | 100 | |||
| SOFA score | ||||||
| ≥8 | 35 | 19 (54.3) | 44 | 0.21 | 1.63 | 0.76 to 3.49 |
| <8 | 41 | 20 (48.8) | 100 | |||
| Empiric antibiotic | ||||||
| Fluoroquinolone | 43 | 17 (39.5) | 46 | <0.01 | 0.36 | 0.17 to 0.77 |
| Nonfluoroquinolone | 34 | 23 (67.6) | 60 | |||
| Bacteremia in the ICU | ||||||
| Yes | 11 | 9 (81.8) | 46 | <0.01 | 3.88 | 1.64 to 9.19 |
| No | 66 | 31 (47.0) | 49 | |||
| TB study in the ICU within 1 week | ||||||
| Yes | 67 | 36 (53.7) | 47.5 | 0.22 | 1.99 | 0.66 to 5.99 |
| No | 10 | 4 (40.0) | 48.5 | |||
| Initiation of ATT in ICU within 2 weeks | ||||||
| Yes | 18 | 10 (55.6) | 68.5 | 0.53 | 1.38 | 0.50 to 3.84 |
| No | 44 | 17 (38.6) | 40 | |||
APACHE, Acute Physiology and Chronic Health Evaluation score; ATT, anti-tuberculosis treatment; SOFA, Sequential Organ Failure Assessment score; TB, tuberculosis.