Figure 7.

Topography in neonatal Tnc^−/− mice. A, B, Coronal serial sections taken every 100 μm from rostral to caudal of olfactory bulb of PND0 Tnc^+/+ (A) and Tnc^−/− (B) mice, stained for Ncam (green) and with the plant lectin DBA (red). DBA binds a subset of OSN axons that project predominantly to the dorsomedial OB (Key and Akeson, 1993). As expected, in Tnc^+/+ mice, DBA+ OSN axons were found predominantly in the dorsal and medial OB. In null mice, DBA+ axons were also observed to target the dorsomedial OB. No obvious differences were observed in the topography of this subset of OSN axons. Scale bar, 250 μm. *Artifact from tissue sectioning.