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. Author manuscript; available in PMC: 2013 Jun 14.
Published in final edited form as: Lab Invest. 2010 Apr 19;90(6):812–823. doi: 10.1038/labinvest.2010.73

Figure 2. Alternative macrophage activation in SSc-ILD.

Figure 2

A, B: Light microscopy of CD14+ peripheral blood monocytes that were cultured in the absence (A) and presence (B) of LPS. C: Overlay of histograms of CD163 staining on cultured CD14+ monocytes. Brown: young control, no LPS. Dark blue: young control +LPS. Green: aged control, no LPS. Red: aged control, +LPS. Light blue: SSc-ILD, no LPS. Purple: SSc-ILD, + LPS. The pink bar indicates the positive gate. D: Percentage of CD14+ cells that express CD163 following 48 hours in culture. White bar: control, black bar: SSc-ILD. E: CCL-18 secretion following 48 hours in culture. White bar: control, black bar: SSc-ILD. *p<0.05, **p<0.01, ***p<0.001. F: IL-10 secretion following 48 hours in culture. White bar: control (n = 27). Black bar: SSc-ILD (n = 12).*p<0.05, **p<0.01, ***p<0.001. All data are expressed as mean ± SEM.

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