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. Author manuscript; available in PMC: 2013 Jun 14.
Published in final edited form as: Cancer Gene Ther. 2011 Sep 2;18(12):837–849. doi: 10.1038/cgt.2011.49

Table 1.

Viral titers from CRC xenografts treated with M51R VSV

Control
2 Days
4 Days
Animal 1 Animal 2 Animal 1 Animal 2 Animal 1 Animal 2
RKO 0 0 3.40×107 6.00×107 1.03×107 1.15×107
LoVo 0 0 5.00×102 3.00×103 0 0

Abbreviations: CRC, colorectal cancer; PBS, phosphate-buffered saline; VSV, vesicular stomatitis virus.

RKO and LoVo xenografts were treated with M51R VSV for the times indicated. The tumors were then homogenized in PBS and viral titers of the supernatants determined as described previously. Sensitive RKO cells support viral replication long after a single treatment with M51R, whereas very low viral titers were seen after a single treatment of LoVo CRC xenografts with M51R virus.