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. 2013 Jun 13;8(6):e66093. doi: 10.1371/journal.pone.0066093

Figure 1. Chimeric proviral strains replicate in vitro in equine cells similar to parental strains.

Figure 1

(A) Schematic illustration of the parental EIAV strains, EV0 and EV13, and the resulting chimeric strains, EVNTerm and EVCTerm. Boxed sites signify the variable regions (numbered 1–8) of the EIAV genome. Blue/green represents EV0-specific genome; Yellow/pink represents EV13-specific genome; = predicted N-linked glycosylation sites. (B) Replication kinetics of parental and chimeric strains is plotted as RT activity (CPM/10 µl supernatant) versus days post-infection. Infections were set up with equivalent MOIs (0.1) of parental and chimeric viruses. Supernatants from infected FEK cells and mock-infected cells were collected every three days and assayed for RT activity.