Table 3.
dbSNP RS ID | Physical position | Location to FAM3C | Allelea | MAFb | MAFc | D’ (r2 ) with rs7776725d | D’ (r2) with rs7776725e |
---|---|---|---|---|---|---|---|
rs4727922 | 120774355 | Downstream | C/T | 0.162 | 0.133 | 1 (0.049) | 0.777 (0.045) |
rs2707461 | 120774586 | Downstream | T/C | 0.188 | 0.142 | 1 (0.053) | 0.822 (0.060) |
rs1803389 | 120776915 | 3′ UTR | T/A | 0.172 | 0.133 | 1 (0.049) | 0.806 (0.052) |
rs2536165 | 120789829 | Intron | C/T | 0.189 | 0.144 | 1 (0.055) | 0.815 (0.059) |
rs2536163 | 120790146 | Intron | A/G | 0.190 | 0.142 | 1 (0.053) | 0.824 (0.061) |
rs2707479 | 120795439 | Intron | C/T | 0.190 | 0.142 | 1 (0.053) | 0.823 (0.061) |
rs1990446 | 120797445 | Intron | C/T | 0.190 | 0.142 | 1 (0.053) | 0.824 (0.061) |
rs2707496 | 120798134 | Intron | T/C | 0.189 | 0.142 | 1 (0.053) | 0.832 (0.062) |
rs12706341f | 120811944 | Intron | T/C | 0.187 | 0.142 | 1 (0.053) | 0.819 (0.059) |
rs718766f | 120812738 | Intron | C/T | 0.269 | 0.242 | 1 (1) | 0.987 (0.937) |
rs7792993f | 120812813 | Intron | C/A | 0.195 | 0.142 | 1 (0.053) | 0.829 (0.063) |
rs7776725 | 120820357 | Intron | C/T | 0.276 | 0.242 | – | – |
rs7793554f | 120820427 | Intron | C/T | 0.457 | 0.383 | 1 (0.513) | 0.996 (0.451) |
The former allele represents the minor allele of each locus
Minor allele frequency calculated in our Caucasian KC-population
Minor allele frequency reported for Caucasians in HapMap
D’ (r2 ) with rs7776725 for Caucasians in HapMap
D’ (r2 ) with rs7776725 in our Caucasian KC-population
Genotypes of these SNPs are only available in KC-population for they are not included in Affymetrix GeneChip 500 K array set