. Author manuscript; available in PMC: 2014 Feb 1.

Published in final edited form as: Hum Genet. 2012 Oct 30;132(2):189–199. doi: 10.1007/s00439-012-1236-5

Table 2.

SNP results of bivariate association for ALM and BSPs (At least one p < 1.00E-05 for each SNP).

SNP	Chromosome	Posision	Allele (minor/ major)	Gene	Predicted function	Discovery Chinese sample			Replication Caucasian sample

						MAF	Bivariate p		MAF	Bivariate p
						MAF	ALM-HBS	ALM-ABS	MAF	ALM-HBS	ALM-ABS
rs4325816	2	174517145	C/T	SP3	intronic	0.02	2.55E-03	7.68E-06	0.22	-	-
rs4145971	4	44537971	T/G	RP11-55C6.1	non-coding	0.25	5.27E-07	-	0.25	-	-
rs961719	4	80247809	C/G		non-coding intronic	0.10	1.01E-05	6.24E-07	0.45	-	-
rs12648730	4	80278147	G/A	RP11-438E5.1	non-coding intronic	0.10	7.95E-06	6.70E-07	0.45	-	-
rs1584984	4	80279231	A/G		non-coding intronic	0.10	6.24E-06	3.43E-07	0.29	-	-
rs11008640	10	32124485	G/C	ARHGAP12	3′ donwstream	0.50	-	3.93E-06	0.19	-	-
rs2768331	10	119245685	C/G	EMX2OS	5′ upstream	0.25	8.15E-06	-	0.22	-	-
rs2507838	11	58229375	A/C		intronic	0.05	1.90E-03	2.06E-06	0.03	5.14E-03	3.71E-04
rs7116722	11	58263484	T/G	GLYAT	3′ donwstream	0.05	7.52E-04	1.75E-06	0.02	1.03E-02	2.23E-03
rs11826261	11	58271739	A/G		3′ donwstream	0.05	3.16E-03	1.75E-06	0.02	1.11E-02	1.89E-03
rs10505721	12	1075963	G/A	ERC1	intronic	0.18	6.44E-07	-	0.13	-	-
rs11068990	12	117471566	G/A	RP11-121J20.1-001	3′ donwstream	0.03	2.52E-05	6.62E-06	0.11	-	-
rs12891306	14	35967587	G/A	SFTA3	3′ donwstream	0.22	7.04E-06	-	0.39	-	-
rs901130	15	72360960	C/G	CCDC33	intronic	0.48	2.22E-03	5.10E-06	0.29	-	-

Phenotype correlation coefficient							0.50^*	0.88^*		0.54^*	0.84^*

Note: - p > 0.05,

p < 0.001,

ALM appendicular lean mass, BSP bone size phenotype, HBS hip bone size, ABS appendicular bone size.