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. Author manuscript; available in PMC: 2013 Jun 14.
Published in final edited form as: J Orthop Res. 2009 Apr;27(4):522–528. doi: 10.1002/jor.20779

Table 1.

Mankin Cartilage Histology Scale

Structure Score Proteoglycan Staining Score
Normal 0 Normal 0
Surface Irregularities 1 Slight Reduction 1
Pannus 2 Moderate Reduction 2
Cleft to Transitional Zone 3 Severe Reduction 3
Cleft to Radial Zone 4 No Dye Noted 4

Cleft to Calcified Zone 5 Cellularity
Complete disorganization 6 Normal 0

Tidemark Integrity Diffuse Hypercellularity 1
Intact 0 Cloning 2
Crossed by Blood Vessels 1 Hypocellularity 3