Skip to main content
. Author manuscript; available in PMC: 2014 May 10.
Published in final edited form as: Biochem Biophys Res Commun. 2013 Apr 10;434(3):439–443. doi: 10.1016/j.bbrc.2013.03.092

Figure 2.

Figure 2

Effects of vinpocetine on ox-LDL uptake and accumulation in macrophages (A–B). Representative images (A) and quantitative data (B) show that vinpocetine inhibits Dil-ox-LDL uptake and accumulation in RAW264.7 cells. RAW264.7 cells were treated with different doses of vinpocetine for 24 h in DMEM containing 0.1% FBS, then loaded with 10 μg/ml Dil-ox-LDL for an additional 4 h. After nuclear staining with DAPI, cellular Dil-ox-LDL was monitored with a fluorescent microscope. Red: Dil-ox-LDL. Blue: DAPI. (C–D) Representative images (C) and quantitative data (D) show that vinpocetine inhibits regular ox-LDL uptake and accumulation as assessed by Oil-red O staining. Cells were observed with bright-field microscopy. Values are means ± SD from at least three independent experiments. *P<0.05 vs. control with vehicle (zero vinpocetine).