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. Author manuscript; available in PMC: 2013 Jun 14.
Published in final edited form as: Chem Res Toxicol. 2012 Jul 6;25(8):1652–1661. doi: 10.1021/tx300113e

Figure 4.

Figure 4

Replication of the 5′-T-(MeFapy-Gua)-T-3′ (2a, top) and unmodified control (2b, bottom) templates by hRev1, the combined activities of hRev1 and yPol ζ with the −1 primer, and extension by yPol ζ with the 0 primer. The dNTP concentrations are for dCTP alone for the hRev1 insertion and for each dNTP for the full-length extension reactions. Results for the 5′-TXG-3′ (1) sequence are part of the Supporting Information (Figure S3).