Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pretreatment with 4% sodium bicarbonate (NaHCO3) prior to cisplatin (NaHCO3/cisplatin) prevented changes in body weight (g) and body temperature (°C) observed in saline/cisplatin-treated groups relative to control/saline groups. Animals received 3 or 4 once weekly injections of cisplatin over (a,c) 16 or (b,d) 28 days, respectively. Data are expressed as mean ± s.e.m. (n = 8–44 per group). * P < 0.045 vs. control/saline or NaHCO3/cispaltin groups.
