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. Author manuscript; available in PMC: 2013 Jun 14.
Published in final edited form as: Prog Retin Eye Res. 2008 May 28;27(4):331–371. doi: 10.1016/j.preteyeres.2008.05.001

Figure 6.

Figure 6

P6 mice were exposed to 20% (A), 40% (B) or 80% (C) oxygen for 36 hours. Retinas were subsequently processed for in situ hybridization with a probe against mouse VEGF mRNA which is pseudo-colored red, while vessels were visualized with an antibody against mouse collagen type IV which is pseudo-colored green. Capillary-free zones around the optic nerve head (dotted yellow lines) and around retinal arteries (arrows) expand with increasing oxygen concentrations. Adapted from Claxton and Fruttiger, 2003.