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Effect of 1 h pretreatment of oral non-micronized SB-705498 on capsaicin provoked nasal secretion. Baseline measurements = pre capsaicin challenge, 10 min data point = 10 min post 0.3 mM capsaicin ipsilateral challenge. (*)P = 0.06; *P < 0.05; **P < 0.001 compared with vehicle pretreatment group, n = 10/12 per group. anova, with Dunnett's follow-up analysis.
