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Effect of 1 h pretreatment of intranasal non-micronized SB-705498 on capsaicin provoked nasal secretion. Baseline measurements = pre capsaicin challenge, 10 min data point = 10 min post 0.3 mM capsaicin ipsilateral challenge. (*)P < 0.07; *P < 0.005; ***P < 0.0001; compared with vehicle pretreatment group, n = 10/12 per group. anova, with Dunnett's follow-up analysis.
