Figure 1.

Effect of Pitolisant (10 mg·kg⁻¹, i.p.) or Modafinil (120 mg·kg⁻¹, i.p.) on dopamine levels in microdialysates of rat nucleus accumbens core. Data are expressed as percentage of the baseline value (A) and in the corresponding AUC over 150 min post administration (B), calculated as the mean amount in the last three samples preceding the drug challenge. Mean ± SEM of n rats. anova followed by a PLSD Fisher test: F(2,17) = 5.883, P = 0.0114 and ^⋆P < 0.05 versus control.