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Venous plasma nitrate concentrations in (A) non-infused arm and (B) infused arm in normal subjects (open symbols) and CHF patients (closed symbols). Baseline nitrate concentrations were greater (P = 0.003) in CHF subjects. During NO2− infusion, nitrate concentrations increased (F = 16.2 P < 0.0001) in the infused arm, but without significant difference between normal subjects and CHF patients.
