Table 1.
Demographic Data for Cases of Psychosis and Controls: Childhood and Adult Characteristics
| Childhood Characteristics | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| 1. Controls | 2. All psychoses† | 3. BP/SAB‡ | 4. Schizophrenia disorders (SD) | Statistical Comparisons | |||||
| (N=101) | (N=99) | (N=35) | (N=45) | ||||||
| Continuous variables† | Mean | SD | Mean | SD | Mean | SD | Mean | SD | |
| Age at interview | 7.02 | 0.1 | 7.05 | 0.2 | 7.05 | 0.1 | 7.07 | 0.2 | NS |
| Maternal age | 26.4 | 6.0 | 25.4 | 6.3 | 25.2 | 5.9 | 25.8 | 6.9 | NS |
| Maternal education, yrs | 11.4 | 2.4 | 10.5 | 2.1 | 10.8 | 2.0 | 10.4 | 2.2 | 1>2* |
| Categorical variables‡ | N | % | N | % | N | % | N | % | |
| Sex: Male | 49 | 48.5 | 59 | 59.6 | 17 | 48.6 | 35 | 77.8 | 1<4**; 3<4** |
| Ethnicity: Non-Caucasian | 6 | 5.9 | 21 | 21.2 | 7 | 20.0 | 10 | 22.2 | 1<2*, 1<3*, 1<4** |
| Parental SES | NS | ||||||||
| 1 – lowest quartile | 21 | 21.7 | 27 | 27.8 | 7 | 20.0 | 14 | 32.6 | |
| 2 | 28 | 28.9 | 24 | 24.7 | 8 | 22.9 | 10 | 23.3 | |
| 3 | 20 | 20.6 | 27 | 27.8 | 11 | 31.4 | 12 | 27.9 | |
| 4 – highest quartile | 28 | 28.9 | 19 | 19.6 | 9 | 25.7 | 7 | 16.3 | |
| Adult characteristics | |||||||||
| Continuous variables† | Mean | SD | Mean | SD | Mean | SD | Mean | SD | |
| Duration of psychosis, yrs | -- | -- | -- | -- | 17.3 | 5.1 | 15.4 | 4.9 | NS |
| Number of psychiatric hospitalizations | -- | -- | -- | -- | 3.6 | 2.4 | 3.5 | 1.6 | NS |
| SANS total | -- | -- | -- | -- | 6.0 | 3.6 | 8.1 | 4.9 | NS |
| SAPS total | -- | -- | -- | 3.8 | 3.4 | 4.7 | 4.3 | NS | |
p<0.05,
p<0.01,
p<0.001. P values from mixed models adjusted for intrafamilial correlation. Variables were log transformed prior to analysis if there were significant skew in the distribution |>0.8|, these variables were Age at Interview, Maternal Age, Number of psychiatric hospitalizations, and SAPS Total.
All psychoses includes major depressive disorder with psychotic features, (N=9), other psychoses (N=10) and groups 3 and 4 for total N=99
BP/SAB is Bipolar Psychosis/Schizoaffective Disorder, Bipolar Type
Maternal age, SES (social-economic status) and Maternal Education calculated at study entry
Sample sizes for adult clinical data on BP/SAB and SD subjects based on available data: Duration of Psychosis (BP/SAB, n = 17, SD, n = 26); Number of Hospitalizations (BP/SAB, n = 32, SD, n = 34); SANS Total,(BP/SAB, n = 24, SD, n = 25); SAPS Total,(BP/SAB, n = 24, SD = 26)