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. Author manuscript; available in PMC: 2013 Jun 14.
Published in final edited form as: Medchemcomm. 2012 Jun;3(6):720–724. doi: 10.1039/C2MD00318J

Figure 2.

Figure 2

HUVEC tube disruption. Effects of a 2 h treatment with (A) Cmpd. 3, (B) Cmpd. 4, and (C) CA4 on a pre-established network of capillary-like tubules formed from HUVECS seeded onto Matrigel™ in a growth factor rich medium over a period of 16 h. CA4 was used as a positive control. All experiments including the vehicle control contained a final concentration of 1% DMSO. These results are representative of the photographic record that was obtained with a minimum of three independent experiments for each compound concentration and observing 9 fields/well (40× objective).