Table 2.

Effect of overall cardiac risk on probability of treatment intensification for elevated blood pressure in diabetic patients.

	High Riska, b		History of MI/CHF
	Odds Ratio (CI)	P value	Odds Ratio (CI)	P value
Model 1: Unadjusted	1.20 (0.80–1.81)	0.37	1.24 (0.83–1.85)	0.29
Model 2: Blood pressure adjustmentc	1.08 (0.71–1.65)	0.73	1.15 (0.76–1.75)	0.50
Model 3: + clinical factors	1.07 (0.70–1.63)	0.77	1.10 (0.72–1.69)	0.66
Model 4: + clinical uncertainty	1.18 (0.76–1.82)	0.46	1.16 (0.75–1.79)	0.51
Model 5: + uncertainty of benefit	1.19 (0.77–1.84)	0.43	1.18 (0.76–1.83)	0.46

Abbreviations: CI = confidence interval, MI = myocardial infarction, CHF = congestive heart failure

^aAll significance testing is compared to Low/Medium Risk Group (individuals with a 10-year UKPDS risk score < 20% and no history of MI or CHF)

^bHigh risk’ includes participants with a 10-year UKPDS risk score > 20%, but no history of patients without a history of MI or CHF

^cModel 2, BP adjustment, adjusts for measured systolic blood pressure (BP) and mean systolic BP in the year before the study

Model 3, clinical factors, adjusts for the variables in Model 1 plus clinical factors (comorbidity scale and number of medications)

Model 4, clinical uncertainty, adjusts for the variables in Model 2 plus clinical uncertainty (self-report of good home blood pressure)

Model 5, uncertainty of benefit, adjusts for the variables in Model 3 plus uncertainty of benefit (use of four blood pressure medications)