Table 1.
Baseline and demographic characteristics by diagnostic group.
| Healthy Control (n = 28) |
MCI (n = 14) |
AD (n = 11) |
|
|---|---|---|---|
| Age | 71.9±9.3 | 73.8±5.2 | 76.3±6.6 |
| Female | 17 (60.7%) | 7 (50%) | 5 (45.5%) |
| Race | |||
| Black | 1 (3.6%) | 0 (0%) | 0 (0%) |
| Asian | 0 (0%) | 0 (0%) | 1 (9.1%) |
| White | 27 (96.4%) | 14 (100%) | 10 (90.9%) |
| Education, years | 15.5±2.0 | 15.6±2.8 | 15.8±3.5 |
| CDR, stage (range 0-3) | 0.0±0.0 | 0.5±0.0*** | 1.1±0.5*** |
| CDR sum of boxes (range 0-15) | 0.0±0.0 | 0.93±0.43*** | 4.82±3.01*** |
| MMSE (range 0-30) | 29.3±1.0 | 26.9±1.8*** | 23.5±3.2*** |
| Boston Naming (range 0-60) | 57.0±3.1 | 53.1±4.2** | 46.5±8.3*** |
| Animal Fluency | 20.5±5.6 | 18.7±5.2 | 12.4±3.3*** |
| AVLT, sum recall (range 0-75) | 52.5±7.9 | 31.6±6.5*** | 25.3±6.5*** |
| AVLT, delay recall (range 0-15) | 10.8±2.6 | 1.8±2.0*** | 1.2±2.0*** |
| Constructional Praxis (range 0-11) | 10.0±1.2 | 9.6±1.1 | 9.2±1.3 |
| CP, delayed recall (range 0-11) | 8.4±2.1 | 5.3±2.2*** | 2.8±3.2*** |
| COWA | 41.1±10.2 | 37.9±9.6 | 27.5±14.8** |
| Trail Making Part A | 31.0±10.5 | 40.2±17.4* | 53.8±24.5*** |
| Trail Making Part B | 75.8±43.2 | 118.8±66.1* | 202.8±106.2*** |
Notes: MCI = Mild Cognitive Impairment, AD = Alzheimer disease, MMSE = Mini-mental State Examination, CDR = Clinical Dementia Rating, AVLT = Auditory Verbal Learning Test, CP = constructional Praxis. Data entries are means and plus-or-minus one standard deviation. Asterisks denote outcomes of t-tests comparing the results of each of the MCI and AD groups to the control group.
*
p < .05,
**
p < .01,
***
p < .001