Table 2.
Modifications to nsrR or the aox promoter regions in suppressor mutants that compensate for the aerobic growth phenotype of the cydAB mutant
| Suppressor mutant | Identified modification |
|---|---|
| OG1 | nsrR: 24 bp (8 amino acid) duplication (amino acids 60–67) |
| OG2 | nsrR: amino acid 96: C to Y (TGC to TAC) |
| OG3 | nsrR: amino acid 63: G to D (GGC to GAC) |
| OG4 | upstream of aox: insertion of a basepair (Fig. 1) |
| OG1-1 | nsrR: premature stop amino acid 52 (GAA to TAA) |
| OG1-2 | nsrR: amino acid 6: F to L (TTC to TTA) |
| OG1-3 | nsrR: amino acid 111: A to E (AAA to GAA) |
| OG1-5 | nsrR: amino acid 96: C to F (TGC to TTC) |
| OG1-6 | nsrR: amino acid 12: R to I (AGA to ATA) |
| OG1-7 | nsrR: premature stop amino acid 94 (GAA to TAA) |
| OG1-9 | nsrR: amino acid 111: A to E (identical to OG1-3) |
| OG1-10 | upstream of aox: insertion of a base pair (Fig. 1) |
| OG1-11 | nsrR: premature stop amino acid 94 (identical to OG1-7) |