Table 3. Representation of coagulation factor genes on the HumanCVD array.
Coagulation factor | Gene symbol | Number of SNPs |
---|---|---|
Fibrinogen | FGA | 23 |
Fibrinogen | FGB | 28 |
Fibrinogen | FGG | 20 |
Prothrombin | F2 | 36 |
Tissue factor | F3 | 38 |
Factor V | F5 | 126 |
Factor VII | F7 | 34 |
Factor VIII | F8 | 19 |
Factor IX | F9 | 18 |
Factor X | F10 | 20 |
Factor XI | F11 | 20 |
Factor XII | F12 | 19 |
Factor XIII | F13A1 | 133 |
Factor XIII | F13B | 9 |
Von Willebrand factor | VWF | 128 |
Prekallikrein | KLKB1 | 21 |
Fibronectin | FN | 0 |
Antithrombin III | SERPINC1 | 9 |
Heparin cofactor II | SERPIND1 | 5 |
Protein C | PROC | 8 |
Protein S | PROS1 | 8 |
Protein Z | PROZ | 6 |
Protein Z-related protease inhibitor (ZPI) | SERPINA10 | 11 |
Plasminogen | PLG | 35 |
Alpha 2-antiplasmin | SERPINF2 | 7 |
Tissue plasminogen activator | PLAT | 19 |
Plasminogen activator | PLAU | 6 |
Plasminogen activator inhibitor-1 | SERPINE1 | 33 |
Plasminogen activator inhibitor-2 | SERPINB2 | 16 |
For each of the main proteins in the coagulation cascade the corresponding gene(s) is/are shown, along with the number of SNPs included in the HumanCVD array for that gene.