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. 2013 Jun 5;13:277. doi: 10.1186/1471-2407-13-277

Table 3.

List of genes differentially expressed between functional p53 and non functional p53 groups

Gene name Chr. position Gene description p-value, p53 functional vs., p53 non functional
PRKCZ
1p36.33-p36.2
Serine threonine kinase involved in several processes such as proliferation, differentiation and secretion.
4.95E-04
 
 
 
↑non functional
LMO3
12p12.3
Lim domain only 3 (rhombotin like 2). Expression of LMO-3 represses p53 mediated mRNA expression of target genes.
1.2E-02
↑non functional
CDKN1A
6p21.2
Cyclin dependent kinase inhibitor. Causes cell cycle arrest in the presence of DNA damage.
1.3E-02↑functional
PDE6A
5q31.2-q34
Phosphodiesterase 6A, cGMP-specific, rod, alpha
7.47E-02
↑non functional
SIAH1
16q12
Seven in absentia homolog 1. Involved in ubiquitination and proteosome related degradation of specific proteins like beta catenin.
2.60E-02
↑non functional
TPD52L2
20q13.2-q13.3
Tumor protein D52 like 2. Expressed in childhood leukemia and testes.
4.65E-02
↑non functional
MDM2
12q14.3-q15
MDM2 p53 binding protein homolog (Mouse)
1.25E-02
↑ functional
HMGCS1 5p14-p13 3-hydroxy 3-methylglutaryl-CoA synthase I 1E-01
↑functional

All p-values are corrected for multiple tests.