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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Endocrinol Metab Clin North Am. 2013 Apr 17;42(2):349–370. doi: 10.1016/j.ecl.2013.02.005

Figure 6.

Figure 6

Correlation between serum osmolality and AVP concentration in 8 young and 8 older subjects during a 2-hour 3% saline infusion following mild dehydration. The older subjects had significantly higher plasma levels of AVP per unit increase in plasma osmolality, strongly suggesting an enhanced osmotically-stimulated secretion. (From Helderman JH. The response of arginine vasopressin to intravenous ethanol and hypertonic saline in man: The impact of aging. J Gerontol 1978;33(1):39-47)