Table 3. MMP-1, -2, and -9 expression measured with the Luminex® system.

	MMP-1 expression [MFI]			MMP-2 expression [MFI]			MMP-9 expression [MFI]
time	control	costunolide	dehydrocostus	control	costunolide	dehydrocostus	control	costunolide	dehydrocostus
[h]			lactone			lactone			lactone
SW-872
24	10749±412	7929±107	18823±1374	2396±290	1190±207	1264±63	229±9	147±22	399±26
48	23809±151	22812±350	23901±113	7215±727	3842±260	1264±63	507±35	253±13	609±35
SW-982
24	24420±166	21375±962	26227±524	251±36	521±98	134±10	27±1	47±5	42±6
48	26972±603	25086±571	27416±578	678±60	920±60	141±132	26±7	52±4	69±6
TE-671
24	34±4	39±10	40±5	160±10	304±118	47±9	41±4	69±32	6±2
48	83±14	74±8	86±4	746±75	879±94	263±20	61±5	78±7	6±2

STS cells were treated with the IC₅₀ concentrations of costunolide or dehydrocostus lactone for 24 and 48 h. Results are represented by mean fluorescence intensity (MFI) and p-values. Bold numbers represent significant differences between control and treated cells (p>0.05).