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. 2013 Jun 14;8(6):e63903. doi: 10.1371/journal.pone.0063903

Figure 5. Phenotype designation reveals differences in gray matter and white matter density.

Figure 5

(A) START subjects (in contrast to controls) had less gray matter volume in the left lingual gyrus extending into the left cuneus (P<0.025) and (B) right pons and right medulla (P<0.02) (C) STOPP subjects (in contrast to controls) demonstrated a trend of less gray matter in the right superior parietal lobule extending into the right precuneus (P<0.07). (D) START subjects had reduced white matter volume (in contrast to STOPP) in the left pons (P<0.004) and (E) left cerebellar tonsil and left pyramis (P<0.012) (F) Analyses also demonstrated START subjects (in contrast to STOPP) had decreased gray matter in the right culmen extending into the right fastigial and left dentate nucleus of the cerebellum (P<0.035). All P values are corrected for age, gender and multiple comparisons using non-stationary cluster correction.