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. 2013 Jun 14;8(6):e66253. doi: 10.1371/journal.pone.0066253

Table 1. Baseline characteristics of the study participants (HIV positive with CD4+ T cell count>350, n = 487).

Parameter IRF1 619 genotype p-value
AA AC CC
% Total number (n = 487) 8.9 43.1 48
% Female 100 100 100
% Kenyan 90 78 69
% Tanzanian 10 21 29
% Ugandan 1 2
Age (median, IQR) 42 (34–46.5) 36 (33–43) 38 (33–43) 0.101
Follow-up, days (median, IQR) 2023 (740–3241) 1462 (351.8–3069.3) 1746 (469.5–3261.5) 0.219
CD4 counts at baseline (median, IQR) 508 (407.2–751.5) 590.5 (447.3–794.8) 576 (455–708.5) 0.508
No. of CD4 counts/participant (median, IQR) 9 (3.5–15.5) 7.5 (3.0–13.8) 8 (3.0–14.0) 0.101
Treatment ART-naïve ART-naïve ART-naïve
% with VL (n = 263)* 10.6 40 49.4
Average log copies/ml (median, IQR) 3.1(1.7–4.0) 3.1(2.0–4.0) 3.0(1.9–4.2) 0.9797
*

Standard of care in Kenya does not include HIV VL; these were analyzed on a random subset of patients (total n = 263).