Table 2. Linear mixed models analyses to determine effect IRF1 619 genotypes have on the rate of CD4+T cell decline in Kenyan FSW cohort with baseline CD4count>350.
Baseline CD4 count | Parameter | Estimate (daily) | P value | 95% Confidence Interval | |
Lower | Upper | ||||
CD4>350 | Follow-up (days) | −.000341 | .000 | −.000410 | −.000273 |
IRF1 619 = AA*follow-up | –1.573174E-5 | .854 | −.000184 | .000153 | |
IRF1 619 = AC*follow-up | –4.424301E-5 | .391 | −.000146 | 5.728030E-5 | |
IRF1 619 = CC*follow-up | 0a | . | . | . |
IRF1 619 genotypes: AA (protective against HIV acquisition); AC, CC (non-protective against HIV acquisition, CC genotype was used as the reference comparison).