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. 2013 Jun 14;8(6):e65605. doi: 10.1371/journal.pone.0065605

Table 4. Affnities of APP-derived peptides for two solubility enhanced mutants of the AIDA1 PTB domain. ND: not done.

Ligand Peptide sequence Kd (µM)
PTBY70A PTB5M
APP-32 ggDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 13.3±1.5 (n = 4) 14.8±1.0 (n = 4)
APP-17 ggQNGYENPTYKFFEQMQN 11.3±1.9 (n = 2) 11.5±1.4 (n = 2)
APP-17{pY} ggQNGYENPT{pY}KFFEQMQN ND >1000(n = 1)