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. 2013 May 9;2(6):596–604. doi: 10.1242/bio.20134952

Fig. 4. Hh-N induces a long-range plateau of Ptc expression in the Drosophila wing disc.

Fig. 4.

(A–C′) Ptc, Cadherin and RFP expression in wing imaginal discs. The expression domain is located above the dashed lines. (A,A′) Control discs: a 10-cell stripe abutting the A/P border expresses Ptc. (B–C′) In ap-Gal4, UAS-RFP, UAS-hh-WT discs, ectopic Ptc is detected at a 10-cell range whereas in ap-Gal4, UAS-RFP, UAS-hh-N Ptc expression expends all throughout the anteroventral quadrant (arrows). (A″–C″) Schematics representing anteroventral quadrants of the above genotypes. Ectopic Ptc is in green. (D) Quantification of ectopic Ptc expression revealing Hh-WT activity gradient and Hh-N longrange plateau (n≥6, for distances >12 µm P-value<0.05). Scale bars: 10 µm.