Table 4.

Consumption of added sugars and endometrial cancer risk by selected characteristics in The EDGE Study.

Sources of Sugar	Cases/Controls	Tertile 1	Tertile 2 OR* (95% CI)	Tertile 3 OR* (95% CI)1	p for heterogeneity
Added sugars (g/1000 kcal)	(Tertile Cutpoints)	(<19.92)	(19.92–32.24)	(>32.24)
Total population	417/395	1.00	1.17 (0.80–1.72)	1.62 (1.09–2.42)
BMI (kg/m2)
<25	105/189	1.00	0.98 (0.49–1.96)	1.79 (0.90–3.58)	0.71
≥ 25	312/206	1.00	1.32 (0.81–2.14)	1.75 (1.04–2.95)
WHR
<0.85	174/208	1.00	0.91 (0.52–1.59)	1.29 (0.70–2.36)	0.18
≥0.85	232/181	1.00	1.83 (1.01–3.30)	2.50 (1.38–4.52)
Physically activity (METs)
<12,2872.5	261/196	1.00	1.08 (0.63–1.88)	1.48 (0.86–2.55)	0.86
≥12,2872.5	154/197	1.00	1.36 (0.76–2.45)	1.64 (0.87–3.08)
No HRT use	335/291	1.00	1.58 (1.00–2.50)	2.03 (1.27–3.26)

OR: Odds Ratio, CI: Confidence Interval, WHR: waist-to-hip ratio

OR*: adjusted for age (continuous), energy intake (continuous), education (high school or less, college, graduate school), race (White, Black, Other, Hispanic), age at menarche (continuous), menopausal status (premenopausal, postmenopausal) and age at menopause for postmenopausal women (<40, 42–54, ≥ 55, unknown), parity (0–1, 2, 3–4), oral contraceptive use (ever, never), HRT use (never, unopposed estrogen only, any combined HRT), BMI (continuous), smoking status (never, past, current) and pack-years for ever smokers (continuous), physical activity (METs for reported average hours per week of moderate or strenuous recreational activities), and diabetes.