. Author manuscript; available in PMC: 2014 Jul 1.

Published in final edited form as: Hum Genet. 2013 Mar 7;132(7):735–743. doi: 10.1007/s00439-013-1277-4

Table 2.

Significant risk SNPs associated with schizophrenia and autism (p <α)

Disease	SNP	Position	Gene	Location	OR	p value	q value	Bioinformatics
Schizophrenia	rs35348915	100467780	Intergenic	Between ADH1B and 1C	1.47	0.0003	0.008
Schizophrenia	rs71612682	100467929	Intergenic	Between ADH1B and 1C	1.47	0.0003	0.008	CpG
Schizophrenia	rs1789892	100469681	Intergenic	Between ADH1B and 1C	1.47	0.0002	0.008	TFBS
Schizophrenia	rs36070167	100469884	Intergenic	Between ADH1B and 1C	1.49	0.0001	0.008
Schizophrenia	rs2866152	100470090	Intergenic	Between ADH1B and 1C	1.48	0.0001	0.008	TFBS
Schizophrenia	rs1612735	100477030	ADH1C	Intron 8	1.40	0.0003	0.009	TFBS
Schizophrenia	rs1442480	100477704	ADH1C	Intron 8	1.41	0.0003	0.008	TFBS/CNV
Schizophrenia	rs1789900	100477740	ADH1C	Intron 8	1.41	0.0003	0.008	TFBS/CNV
Schizophrenia	rs1442481	100478070	ADH1C	Intron 8	1.40	0.0003	0.009	Conserved
Schizophrenia	rs1789901	100478392	ADH1C	Intron 8	1.42	0.0001	0.008	TFBS
Schizophrenia	rs1662060	100478864	ADH1C	Intron 8	1.43	0.0001	0.008	TFBS
Schizophrenia	rs1789904	100481431	ADH1C	Intron 6	1.44	0.0001	0.008	TFBS
Schizophrenia	rs1789906	100482242	ADH1C	Intron 6	1.43	0.0001	0.008	TFBS
Schizophrenia	rs904094	100482275	ADH1C	Intron 6	1.43	0.0001	0.008
Schizophrenia	rs1789912	100482965	ADH1C	Intron 6	1.43	0.0001	0.008	TFBS/CpG/Conserved
Schizophrenia	rs1789916	100485719	ADH1C	Intron 3	1.45	8.9 × 10⁻⁵	0.008	TFBS/CpG/CNV
Schizophrenia	rs1693427	100485850	ADH1C	Intron 3	1.46	8.9 × 10⁻⁵	0.008	TFBS
Schizophrenia	rs1693428	100485954	ADH1C	Intron 3	1.45	0.0001	0.008	TFBS
Schizophrenia	rs1154434	100504035	Intergenic	11 kb to 5′ of ADH1C	1.52	0.0002	0.008	TFBS
Autism	rs62323588	100240894	Intergenic	Between ADH5 and 4	1.50	2.4 × 10⁻⁵	0.012	Long RNA
Autism	rs2213041	100466374	Intergenic	Between ADH1B & 1C	1.33	0.0003	0.026	TFBS
Autism	rs1789889	100466888	Intergenic	Between ADH1B and 1C	1.33	0.0003	0.026	TFBS
Autism	rs2226898	100467950	Intergenic	Between ADH1B and 1C	1.33	0.0003	0.026	TFBS
Autism	rs1789890	100468907	Intergenic	Between ADH1B and 1C	1.33	0.0003	0.026	TFBS
Autism	rs1229863	100471409	Intergenic	Between ADH1B and 1C	1.33	0.0003	0.026	Conserved

Conserved located at a species-conserved element, TFBS located at a transcription factor binding site, CpG located at a methylated CpG island, CNV located at a copy number variant (CNV), long RNA located at a long RNA transcript (>200 bases)