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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Cytokine. 2013 May 8;63(1):6–9. doi: 10.1016/j.cyto.2013.04.015

Figure 1. Th17 polarizing cytokines failed to induce IL-17 from antigen-specific Th1 clones.

Figure 1

(A) MOG35-55- and HSV-specific T cell clones were stimulated with PMA and ionomycin and intracellular IFN- and IL-17 were evaluated by flow cytometry (representative of three experiments). (B) MOG35-55- and HSV-specific T cell clones were respectively stimulated by each antigen with or without addition of IL-1, IL-6, IL-23 and anti-IFN- . IL-17 level in the supernatant was quantified by ELISA (pooled data of 4 experiments).