Table 1.
Patient Characteristics and CMR Variables Grouped by Tertiles of Age
| Cohort (32) | Age < 40 (10) | Age 40–60 (11) | Age > 60 (11) | p Value | |
|---|---|---|---|---|---|
| Mean Age (yrs) | 49 (15) | 31 (7) | 51 (5) | 65 (5) | <0.001 |
| Female (number, %) | 17 (56) | 5 (50) | 6 (55) | 7 (70) | 0.23 |
| Body Mass Index (kg/m2) | 26 (6) | 24 (4) | 28 (6) | 27 (6) | 0.27 |
| Systolic Blood Pressure (mmHg) | 120 (11) | 111 (11) | 121 (11) | 125 (6) | 0.31 |
| Diastolic Blood Pressure (mmHg) | 74 (7) | 72 (5) | 72 (8) | 74 (5) | 0.72 |
| Heart Rate (beats/minute) | 68 (11) | 63 (13) | 68 (8) | 68 (9) | 0.56 |
| LVEDV (ml) | 133 (24) | 142 (23) | 141 (20) | 118 (27) | 0.12 |
| LVESV (ml) | 48 (15) | 50 (17) | 51 (9) | 43 (15) | 0.24 |
| Septal Wall Thickness (mm) | 8 (1) | 6 (1) | 7 (1) | 8 (1) | 0.24 |
| Lateral Wall Thickness (mm) | 7 (1) | 7 (1) | 7 (1) | 7 (1) | 0.24 |
| LV Mass Index (g/m2) | 45 (7) | 41 (9) | 46 (4) | 47 (8) | 0.23 |
| RVEDV (ml) | 131 (31) | 154 (27) | 138 (24) | 113 (25) | 0.009 |
| RVESV (ml) | 61 (10) | 76 (8) | 59 (8) | 55 (11) | 0.015 |
| Indexed Max LA Volume (ml/m2) | 33 (10) | 29 (9) | 33 (10) | 37 (8) | 0.12 |
| LVEF (%) | 64 (7) | 64 (9) | 64 (14) | 63 (7) | 0.66 |
| RVEF (%) | 53 (4) | 51 (5) | 56 (7) | 51 (5) | 0.53 |
| ECV | 0.28 (0.03) | 0.25 (0.02) | 0.27 (0.03) | 0.31 (0.02) | <0.001 |
All data are mean (SD) unless otherwise indicated; LVEDV = left ventricular end diastolic volume; LVESV = left ventricular end systolic volume; RVEDV = right ventricular end diastolic volume; RVESV = right ventricular end systolic volume; LVEF = left ventricular ejection fraction; RVEF = right ventricular ejection fraction; ECV = myocardial extracellular volume fraction derived from quantitative T1 measurements;