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. Author manuscript; available in PMC: 2014 Jul 10.
Published in final edited form as: J Control Release. 2013 Apr 6;169(0):17–27. doi: 10.1016/j.jconrel.2013.03.033

Fig. 4. The in vitro cytotoxicity of 4-(N)-GemC8-SLNs and 4-(N)-GemC18-PLGA-NPs in TC-1-GR cells.

Fig. 4

(A) The IC50 values of the 4-(N)-GemC8-SLNs and 4-(N)-GemC18-SLNs in TC-1-GR cells (n = 4). aP < 0.01. (B) The cytotoxicity of the 4-(N)-GemC18-PLGA-NPs in TC-1-GR cells after 48 h of incubation (n = 5). bP < 0.001. (C) The release profiles of GemC18 or GemC8 from 4-(N)-GemC18-PLGA-NPs, 4-(N)-GemC18-SLNs, or 4-(N)-GemC8-SLNs (n = 2–3).

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