Table 5.
The associations between 5 independent SNPs in the FTO gene and the risk of melanoma 1
| SNP | Reference allele | Test allele | OR(95% CI) | P |
|---|---|---|---|---|
| rs12933928 | A | G | 0.85 (0.74–0.97) | 0.01 |
| rs12932428 | C | T | 0.88 (0.77–0.98) | 0.02 |
| rs1125338 | T | C | 0.89 (0.80–1.00) | 0.04 |
| rs12599672 | T | A | 1.17 (1.01–1.36) | 0.03 |
| rs12600192 | C | G | 1.19 (1.06–1.33) | 0.004 |
These analyses were conducted using logistic regression models among 2,830 samples in the MD Anderson melanoma case-control study, adjusting for top two eigenvectors.