. Author manuscript; available in PMC: 2013 Jun 15.

Published in final edited form as: Eur J Endocrinol. 2010 Jun 7;163(3):399–406. doi: 10.1530/EJE-10-0021

Table 1.

Clinical and biochemical variables in women with PCOS and normal, control women according to BMI staus.

Variable	Lean control	Obese control	Lean PCOS	Obese PCOS	P-value
n	21	38	21	43	N/A
Age (yrs)	21.9 (18.7–25.0)	26.0 (23.7–28.3)	22.9 (19.7–26.0)	25.9 (23.7–28.0)	0.08
BMI (kg/m²)	20.5 (18.8–22.2) ^a,^c	30.9 (29.6–32.2) ^b,^d	20.0 (18.3–21.7) ^a,^c	29.8 (28.6–31.0) ^b,^d	<0.0001
Percent body fat (%)	23.1 (20.4–25.9) ^a,^c	42.7 (40.7–44.8) ^b,^d	24.8 (22.0–27.5) ^a,^c	43.3 (41.4–45.2) ^b,^d	<0.0001
Waist circumference (cm)	66.1 (61.8–70.3) ^a,^c	92.4 (89.2–95.6) ^b,^d	67.8 (63.6–72.1) ^a,^c	90.3 (87.4–93.3) ^b,^d	<0.0001
Hip circumference (cm)	86.7 (83.3–90.1) ^a,^c	105.8 (103.3) ^b,^d	86.9 (83.5–90.3) ^a,^c	102.3 (99.9–104.7) ^b,^d	<0.0001
WHR	0.76 (0.74–0.79) ^a,^c	0.87 (0.85–0.89) ^b,^d	0.78 (0.76–0.80) ^a,^c	0.88 (0.87–0.90) ^b,^d	<0.0001
Total cholesterol (mmol/L)	3.56 (3.27–3.85) ^a,^b,^c	4.16 (3.95–4.38) ^c,^d	4.44 (4.15–4.74) ^d	4.69 (4.49–4.89) ^a,^d	<0.0001
HDL cholesterol (mmol/L)	1.24 (1.10–1.38)	1.21 (1.10–1.31)	1.43 (1.29–1.57)	1.31 (1.21–1.40)	0.08
LDL cholesterol (mmol/L)	2.29 (2.21–2.38) ^a,^c	2.84 (2.63–3.04) ^d	2.68 (2.38–2.97)	2.97 (2.70–3.24) ^d	0.003
Triglycerides (mmol/L)	0.96 (0.68–1.23) ^c	1.32 (1.13–1.52)	1.09 (0.82–1.35) ^c	1.65 (1.47–1.84) ^b,^d	0.0001
Fasting insulin^* (mIU/L)	9.98 (8.37–11.90) ^a,^c	20.14 (17.67–22.95) ^b,^d	10.01 (8.39–11.93) ^a,^c	18.84 (16.67–21.31) ^b,^d	<0.0001
Fasting glucose (mmol/L)	4.33 (4.20–4.47) ^a,^c	4.77 (4.61–4.94) ^c,^d	4.69 (4.53–4.85) ^c	5.09 (4.87–5.31) ^a,^b,^d	<0.0001
HOMA-IR^*	1.92 (1.59–2.32) ^a,^c	4.25 (3.69–4.89) ^b,^d	2.03 (1.38–2.45) ^a,^c	4.22 (3.70–4.83) ^b,^d	<0.0001
Total testosterone (nmol/L)	1.97 (1.49–2.46) ^b	2.30 (1.94–2.66) ^b	3.21 (2.73–3.70) ^a,^c,^d	2.38 (2.04–2.72) ^b	0.003
SHBG (nmol/L)	63.34 (59.06–67.62) ^a,^b,^c	41.92 (38.02–45.81) ^c,^d	46.92 (42.04–51.80) ^c,^d	31.55 (28.84–34.18) ^a,^b,^d	<0.0001
Free testosterone^* (pmol/L)	22.82 (18.52–28.12) ^b,^c	31.99 (27.39–37.36) ^b	47.48 (38.54–58.50) ^a,^d	41.42 (35.80–47.92) ^d	<0.0001

Data are means (95% CI) unless noted.

Geometric means.

BMI - body mass index, HDL - high density lipoprotein, HMW - high molecular weight, HOMA-IR - homeostasis model assessment - insulin resistance index, P-value for ANOVA for difference between groups.

<0.05 compared to obese control,

<0.05 compared with lean PCOS,

<0.05 compared with obese PCOS,

<0.05 compared to lean control

To convert cholesterol to mg/dL, divide by 0.02586; to convert triglycerides to mg/dL, divide by 0.01129; to covert glucose to mg/dL:, divide by 0.05551; to convert total testosterone to ng/ml, divide by 3.467; to convert free testosterone to pg/ml, divide by 3.467.