Table 2.
Plasma biomarker concentration in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass (CABG with CPB) or off pump coronary artery bypass (OPCAB)
| All patients (n = 25) | CABG with CPB (n = 16) | OPCAB (n = 9) | P-value | |
|---|---|---|---|---|
| sRAGE, 0 h, pg/ml | 765 (246) | 659 (221) | 771 (233) | 0.273 |
| sRAGE, 4 h, pg/ml | 1976 (671)* | 2145 (632)* | 1732 (634)* | 0.432 |
| S100A12, 0 h, ng/ml | 85 (65) | 88 (49) | 68 (62) | 0.385 |
| S100A12, 4 h, ng/ml | 3458 (420)* | 2956 (379)* | 3638 (420)* | 0.276 |
| Il-6, 0 h, pg/ml | 14 (21) | 13 (19) | 14 (22) | 0.456 |
| IL-6, 4 h, pg/ml | 431 (210)* | 386 (194)* | 482 (170)* | 0.441 |
| MPO, 0 h, ng/ml | 9.4 (4.8) | 8.3 (3.8) | 9.6 (4.6) | 0.391 |
| MPO, 4 h, ng/ml | 23.5 (11.8)* | 24.6 (9.2)* | 22.6 (8.7)* | 0.456 |
| TNF-α, 0 h, pg/ml | 5.2 (4.1) | 5.1 (3.7) | 4.7 (3.6) | 0.415 |
| TNF-α, 4 h, pg/ml | 9.6 (4.1)* | 9.5 (4.1)* | 9.7 (3.9)* | 0.562 |
| CRP, 0 h, μg/ml | 0.9 (1.3) | 0.9 (1.1) | 0.8 (1.2) | 0.432 |
| CRP, 4 h, μg/ml | 1.4 (3.1) | 1.8 (2.2) | 1.3 (2.6) | 0.643 |
Values are mean ± (SD).
*
p < 0.05 compared to time respective point 0 h.
(sRAGE, soluble receptor for advanced glycation end products; IL-6, interleukin-6; MPO, myeloperoxidase; TNF-α, tumor necrosis factor alpha; CRP, C-reactive protein).