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. Author manuscript; available in PMC: 2014 May 6.
Published in final edited form as: Mol Pharm. 2013 Apr 22;10(5):1977–1987. doi: 10.1021/mp4000019

Figure 8.

Figure 8

Biodistribution of curcumin and its metabolites 15 min and 60 min post i.v. administration of (A) nanocurcumin (equivalent to 10 mg/kg curcumin) and (B) solvent solubilized curcumin (10 mg/kg) to SD rats. Data are mean ± S.D., n = 3 rats. Plasma and tissue samples were collected at 15 min and 60 min postdose. The %ID of curcumin and metabolites in plasma was calculated as: (curcumin or metabolite molar concentration × total plasma volume)/total molar dose × 100%. The %ID of curcumin and metabolites in tissues was calculated as: (curcumin or metabolite molar concentration × tissue mass)/total molar dose × 100%.