Table 4.
Adjusted Cox proportional hazards regression showing the relation of baseline and time-varying ICED score with risk of first and total hospitalizationsa
| First hospitalizations
|
Repeated hospitalizations
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Baseline ICED score
|
Time-varying ICED score
|
Baseline ICED score
|
Time-varying ICED score
|
|||||
| b (SE) | HR (95% CI) | b (SE) | HR (95% CI) | b (SE) | HR (95% CI) | b (SE) | HR (95% CI) | |
| ICED score (per 1 unit) | 0.14 (0.03) | 1.15 (1.08–1.23) | 0.15 (0.03) | 1.17 (1.09–1.25) | 0.17 (0.02) | 1.19 (1.14–1.24) | 0.21 (0.02) | 1.24 (1.18–1.29) |
| Age (per 10 y) | 0.06 (0.02) | 1.06 (1.02–1.10) | 0.06 (0.02) | 1.06 (1.02–1.10) | 0.05 (0.01) | 1.05 (1.02–1.08) | 0.04 (0.01) | 1.04 (1.01–1.07) |
| Female sex | 0.13 (0.06) | 1.14 (1.02–1.27) | 0.13 (0.06) | 1.14 (1.02–1.27) | 0.20 (0.04) | 1.22 (1.14–1.31) | 0.20 (0.04) | 1.22 (1.13–1.31) |
| Black race | −0.12 (0.06) | 0.89 (0.79–1.01) | −0.12 (0.06) | 0.89 (0.79–1.01) | −0.008 (0.04) | 0.99 (0.91–1.08) | −0.004 (0.04) | 1.00 (0.99–1.01) |
| Diabetes | 0.16 (0.06) | 1.17 (1.04–1.30) | 0.14 (0.06) | 1.16 (1.04–1.30) | 0.16 (0.04) | 1.18 (1.09–1.27) | 0.16 (0.04) | 1.18 (1.09–1.26) |
| Vintage (per 1 y) | 0.008 (0.006) | 1.01 (1.00–1.02) | 0.007 (0.006) | 1.01 (1.00–1.02) | 0.002 (0.005) | 1.00 (0.99–1.01) | 0.001 (0.004) | 1.00 (0.99–1.01) |
| Serum albumin (per 0.1 g/dL) | −0.05 (0.008) | 0.95 (0.94–0.97) | −0.05 (0.008) | 0.95 (0.94–.0.97) | −0.04 (0.005) | 0.96 (0.95–0.97) | −0.04 (0.005) | 0.96 (0.95–0.97) |
a
Models adjusted for each of the other listed variables and intervention group and stratified by clinical center.
HR=hazard ratio; CI=confidence interval; ICED=Index of Coexistent Diseases; SE=standard error