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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Biochim Biophys Acta. 2012 Jul 24;1831(1):126–132. doi: 10.1016/j.bbalip.2012.07.012

Figure 2. Proposed role of lipid phosphate phosphatases in regulating lysophospholipid signaling.

Figure 2

Bioactive lysophosphatidic acid (LPA) production is the result of autoxatin mediated hydrolysis of lysophopshatidyl choline (LPC) generated at least in part from phosphatidyl choline (PC). Extracellular LPA can act via its G-protein coupled receptors to elicit intracellular signaling and/or be degraded by surface LPPs to receptor inactive monoacyl glycerol.