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. Author manuscript; available in PMC: 2013 Jun 17.
Published in final edited form as: Neurobiol Dis. 2008 Mar 10;30(3):312–322. doi: 10.1016/j.nbd.2008.01.015

Figure 5.

Figure 5

Sertraline increases neurogenesis in subventricular zone (SVZ) of mice. Mice were administered sertraline at 10 mg/kg from 12 weeks of age for 4 weeks. Mice were perfused at 3 days after the last BrdU injection for cell proliferation study indicating BrdU-positive cells in SVZ (a) and 3 weeks after the last injection for quantifying survival of newly generated cells indicated by remaining BrdU-positive cells (b). All values are the mean and SE. n=4 mice per group. *p<0.05, compared to the values of nontg vehicle group, **p<0.05 compared to the values of HD vehicle group by standard student t-tests.