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Effects of gestational BPA exposure on DNA methylation of Esr1 exon A. (A) Schematic of the regulatory region of the human (ESR1) and mouse (Esr1) gene. Percentages represent the degree of homology between these two species. Methylation of 11 CpG sites in exon A (Fig. S2) was examined in the male (B) and female (C) prefrontal cortex and male (D) and female (E) hypothalamus at PND 28 (n = 6 per sex per brain region per treatment) following in utero exposure to vehicle or 20 µg/kg BPA.
