Table 1.
Summary of PfMSH2-1 and PfMSH2-2 dominant mutator assays using the lacZ− CC108 strain.
Experiment no. | Constructa | Lac+ median reversion frequency | Fold Increaseb |
---|---|---|---|
pBS | 1.6 × 10−9 | ||
1 | hMSH2 | 8.9 × 10−9 | 5.7 |
pBS | 2.9 × 10−8 | ||
2 | PfMutS2-2 | 6.7 × 10−8 | 2.3 |
pBS | 4.3 × 10−8 | ||
3 | PfMutS2-2 | 2.4 × 10−7 | 5.6 |
Thirteen cultures were assayed for each construct.
Relative to pBS control.